Endocrine Abstracts

The suprachiasmatic nucleus (SCN) is the ‘master clock’ of the mammalian brain. It coordinates the peripheral clock in body, including the pineal clock that receives SCN input via a multisynaptic noradrenergic pathway. Melatonin is exclusively involved in signaling the ‘time of day’, ‘time of year’ to all tissues and is thus considered to be the chronological pacemaker or ‘zeitgeber’.Objective: To determine the chr...

The correction of a subtle nutritional deficiency that may reduce the risk of a future chronic disease is indeed a challenge. One of the most intriguing current and future impacts on public health may come from a greater intake of omega-3 fatty acids such as α-linolenic acid (ALA).Objective: We investigated the effect of an increased amount of dietary α-linolenic acid (ALA) from enriched eggs on the lipid profile and inflammatory markers in hea...

To examine the hormonal characteristics related to age of reproductive axis, serum hormone profiles and inhibins A and B were investigated in fertile and menopausal women.Subjects: Forty-three cycling women (23–40-year-old) and 75 menopausal women (55–70-year-old) were studied. Serum 17-OHP, DHEA, DHEAS, androstendion, estradiol, estrone, progesterone, testosterone, free testosterone, DHT, SHBG, inhibin A and inhibin B, LH, FSH, Prl, TSH, GH, I...

Objective: The present study examined the influence of light and dark, seasonal differences, electromagnetic fields, adrenergic and GABA-ergic control, age on melatonin secretion and also which factors affect rhythmicity of melatonin secretion, both in health and disease.Data were combined from a series of studies conducted between 1997 and 2006. Hormones were temporally assayed by immunometric assays.The results showed that melato...